‘The Interview’: The Darker Side of Julia Louis-Dreyfus

At some point in almost every performance she gives, Julia Louis-Dreyfus has this look. If you’ve watched “Seinfeld,” “The New Adventures of Old Christine” or “Veep,” you know it — the perfect mix of irritation and defiance. As if she were saying, Try me.

Louis-Dreyfus’s performances in those shows — from the eccentrically self-actualized Elaine Benes in “Seinfeld” to the completely un-self-aware Selina Meyer in “Veep” — were comedic master classes. But in recent years, she has been moving toward more introspective and serious work. Still, that “try me” vibe remains. She hosts a wonderful hit podcast called “Wiser Than Me,” in which she interviews older, famous, often (necessarily) sharp-elbowed women — Billie Jean King, Sally Field, Carol Burnett and Debbie Allen, to name a few — about their lives and careers and the crap they’ve all navigated. Last year she starred as a frustrated novelist and wife in the writer-director Nicole Holofcener’s movie “You Hurt My Feelings,” the second collaboration between the two women about the struggles of middle age. In her newest movie, “Tuesday,” which opens nationwide on June 14, Louis-Dreyfus plays a mother whose teenage daughter has a terminal illness. It’s a surreal, dark fairy tale that she was nervous about taking on. (She’s also got a recurring role in the Marvel Cinematic Universe: She was shooting “Thunderbolts” when we talked.)

At 63, Louis-Dreyfus says she’s still trying to prove herself (“always”), and that “Tuesday” is part of that process. “I’m certain nobody would have considered me for that role 20 years ago, and that’s probably because they just thought of me only as a ‘ha-ha’ funny person.” She’s still interested in TV comedy, she told me, but she’s loving this stage of her career, and getting to do more. “I just want to try it all,” she says. “It’s good for my brain.”

You’re in a new Marvel film at the moment. It must be a very different kind of set to be on. What’s it like? It’s very well organized. Very methodical. And I don’t mean that in a negative way. Particularly on this film, they’re very much focused on, frankly, the human story, believe it or not. They’re trying to sort of go back to their roots, as it were. And so there’s a lot of focus on that. They’re trying to stay away from as much C.G.I. or whatever as possible, so that the stunts are, like, everywhere. And in fact, I had to do a couple.

What stunts have you done? Well, I’m making this out to sound like I’m flying through the air like Captain America or whatever, but I’m not. It’s just a very, very, very, very brief stunt.