More stories

  • in

    The Long, Long Wait for a Diabetes Cure

    In the three decades since she was first diagnosed with Type 1 diabetes, Lisa Hepner has clung to a vague promise she often heard from doctors convinced medical science was on the cusp of making her body whole again. “Stay strong,” they would say. “A cure is just five years away.”But the cure has yet to arrive, and Ms. Hepner, 51, a filmmaker from Los Angeles, remains hobbled by her body’s inability to make insulin, the sugar-regulating hormone produced by the pancreas. “I might look fine to you,” she said, “but I feel crappy 70 percent of the time.”Staying healthy can be exhausting for many of the 37 million Americans with some form of diabetes. There’s the round-the-clock monitoring of sugar levels; the constant, life-sustaining insulin injections; and the potential threats from diabetes’ diabolical complications: heart disease, blindness, kidney damage and the possibility of losing a gangrenous limb to amputation.“‘The cure is five years away’ has become a joke in the diabetes community,” Ms. Hepner said. “If it’s so close, then what’s taking so long? And in the meantime, millions of us have died.”That attenuated sense of hope drove Ms. Hepner to spend nearly a decade following the fortunes of ViaCyte, a small San Diego biotech company working to create what would essentially be an artificial pancreas. If successful, its stem-cell-derived therapy would eliminate the pin-pricks and insulin injections that circumscribe the lives of the 1.5 million Americans with Type 1 diabetes. Vertex Pharmaceuticals, a Boston biotech company developing a similar therapy, has already made significant headway.Since its theatrical debut in June, “The Human Trial,” the documentary she produced with her husband, Guy Mossman, has electrified the diabetes community, especially those with Type 1, a disease that the uninitiated often conflate with the more common Type 2.Unlike Type 2, which tends to emerge slowly in adulthood and can sometimes be reversed early on with exercise and dietary changes, Type 1 is an autoimmune disease that often strikes without warning in childhood or adolescence.Type 1 is also far less prevalent, affecting roughly 10 percent of those with diabetes. A pancreas transplant can cure the disease, but donated organs are in short supply and the surgery carries substantial risks. In most years, only a thousand transplants are done in the United States. To ensure the body does not reject the implanted pancreas, recipients must take immunosuppressant drugs all their lives, making them more susceptible to infections.Maren Badger, one of the first patients to have experimental cell colonies implanted under her skin, in a scene from the film.AbramoramaTherapies developed from human embryonic stem cells, many experts say, offer the best hope for a lasting cure. “The Human Trial” offers a rare glimpse into the complexities and challenges of developing new therapies — both for the patients who volunteer for the grueling clinical trials required by the Food and Drug Administration, and for the ViaCyte executives constantly scrambling to raise the money needed to bring a new drug to market. These days, the average cost, including the many failed trials along the way, is a billion dollars.At a time when the soaring price of insulin and other life-sustaining drugs has tarnished public perceptions of the pharmaceutical industry, the film is also noteworthy for its admiring portrayal of a biotech company whose executives and employees appear genuinely committed to helping humanity. (Limiting the cost of insulin remains politically volatile. On Sunday, during a marathon vote on the Democrats’ climate and health bill, Republicans forced the removal of a provision with a $35 cap on insulin prices for patients with private insurance, though the cap remained in place for Medicare patients.)“The Human Trial,” which can also be viewed online, has become a rallying cry for Type 1 patients, many of whom believe only greater visibility can unleash the research dollars needed to find a cure.Those who have seen the film have also been fortified by seeing their own struggles and dashed hopes reflected in the journeys of the film’s two main subjects, Greg Romero and Maren Badger, who became among the first patients to have the experimental cell pouches implanted under their skin.The despair that drives them to become human guinea pigs can be hard to watch. Mr. Romero — whose father also had the disease, went blind before he was 30 and then died prematurely — confronts his own failing vision while grappling with the pain of diabetes-related nerve damage. “I hate insulin needles, I hate the smell of insulin. I just want this disease to go away,” Mr. Romero, 48, says numbly at one point in the film.Type 1 can leave patients feeling alienated and alone, in part because of flawed assumptions about the disease. Tim Hone, 30, a medical writer in New York who has been living with Type 1 since he was 15, said friends and acquaintances sometimes suggested that he was responsible for causing his illness. “I’ve had people scold me and say that if I went on a diet and stopped eating Snickers bars I could reverse my disease,” Mr. Hone said.The stigma often drives people with Type 1 to hide the disease. In his quest to feel “normal” at college, Todd Boudreaux said, he avoided telling friends about his illness, a decision that could have had dangerous ramifications in the event of a seizure brought on by low blood sugar levels.Greg Romero, one of the subjects in the documentary. “I hate insulin needles, I hate the smell of insulin. I just want this disease to go away,” he said.Abramorama“I didn’t want to be defined by my illness, and I didn’t want to be seen as weak, but having Type 1 does make you different and it’s important that everyone around knows so they can help if you have severe low blood sugar,” said Mr. Boudreaux, 35, who lives in Monterey, Calif., and works for the nonprofit group Beyond Type 1.Ms. Hepner, too, has spent much of her life downplaying the disease, even with her husband, Mr. Mossman. She recalled his confusion early in their relationship when he awoke to find her discombobulated and drenched in sweat, the result of hypoglycemia, or low blood sugar. The more Mr. Mossman, a cinematographer, learned about the disease, the more he pressed her to make the film.For years, Ms. Hepner stood her ground, worried about drawing unwanted attention to her health. “It’s a competitive world out there and I just didn’t want people to think, ‘Oh, she’s not thinking straight because her blood sugar is high,’” she said.But over time, the ubiquity of pink-ribbon breast cancer awareness campaigns and highly publicized efforts to cure Alzheimer’s made Ms. Hepner realize her filmmaking skills could change public perceptions of Type 1, a disease that is nearly invisible, in part because many people who have it do not look sick.She hopes to change other misperceptions, including the notion that diabetes is a relatively inconsequential and “manageable” illness, one that has been popularized by Big Pharma’s feel-good drug television commercials that feature self-assured patients playing tennis and basketball and piloting hot air balloons.In fact, the industry spends a fraction of its research dollars on finding a cure, with the rest directed toward developing medications and devices that make it easier to live with the disease, according to the Juvenile Diabetes Cure Alliance.The payoff from those investments is undeniable. For those who can afford them, continuous glucose-monitoring devices can obviate the need for self-administered finger-prick testing, and the machines can be paired with iPhone-size insulin pumps that eliminate much of the guesswork over dosing.Ms. Hepner with her son Jack in a scene from the film. “We need to stop trying to normalize this disease because, let’s face it, having diabetes isn’t normal,” she said.AbramoramaMs. Hepner has profound appreciation for the wonders of insulin: At one point in the film she pays homage to its inventor, Frederick Banting, during a visit to his home in Canada. But she notes that insulin-dependent diabetes is no picnic. Many people without insurance cannot afford the thousands of dollars it costs annually for the drug, forcing some to skimp and ration. And a miscalculated or ill-timed dose can lead to seizures, unconsciousness and even death. Even with all the advances in care, only about 20 percent of adults with Type 1 are able to maintain healthy blood sugar levels, according to a 2019 study. On one occasion, Ms. Hepner woke up in the I.C.U. after her insulin pump failed.“We need to stop trying to normalize this disease because, let’s face it, having diabetes isn’t normal,” she said. “It’s the other pandemic, one that killed 6.7 million people last year around the world.”Despite her frustrations, it would be inaccurate to describe Mr. Hepner and her film as pessimistic. At the risk of giving away too much, “The Human Trial” ends on a hopeful note. And despite a number of near-brushes with bankruptcy, ViaCyte succeeded in gaining the funding to keep the laboratory lights burning.Then there is more recent news that did not make it into the film. Last month, ViaCyte was acquired by Vertex, the competing biotech company that has been developing its own stem-cell treatment. That treatment has shown early success, and last year the company announced that a retired postal worker who took part in clinical trials had been cured of Type 1 diabetes.After almost a lifetime of hearing a cure was just around the corner, Dr. Aaron Kowalski, chief executive of the JDRF (Juvenile Diabetes Research Foundation), the world’s biggest funder of Type 1 research, counts himself as an optimist. A dozen more drug companies are pursuing a cure than a decade ago, he said, and the organization this year plans to spend $100 million on cure research. “It’s not a matter of if this will happen, it’s a matter of when,” said Dr. Kowalski, who is a scientist and has had the disease since childhood, as has a younger brother. “Our job is to make sure it happens faster.”Until that day, he added, people with diabetes, both Type 1 and Type 2, could use a little empathy and understanding. More

  • in

    Tree Rings Shed Light on a Stradivarius Mystery

    Analyses of 17th-century stringed instruments suggest that a young Antonio Stradivari might have apprenticed with a particular craftsman.History is revealed in tree rings. They have been used to determine the ages of historical buildings as well as when Vikings first arrived in the Americas. Now, tree rings have shed light on a longstanding mystery in the rarefied world of multimillion-dollar musical instruments.By analyzing the wood of two 17th-century stringed instruments, a team of researchers has uncovered evidence of how Antonio Stradivari might have honed his craft, developing the skills used in the creation of the rare, namesake Stradivarius violins.Mauro Bernabei, a dendrochronologist at the Italian National Research Council in San Michele all’Adige, and his colleagues published their results last month in the journal Dendrochronologia, and their findings are consistent with the young Stradivari apprenticing with Nicola Amati, a master luthier roughly 40 years his senior. Such a link between the two acclaimed craftsmen has long been hypothesized.In the 17th and early 18th centuries, Stradivari created stringed instruments renowned for their craftsmanship and superior sound. “Stradivari is generally regarded as the best violin maker who ever lived,” said Kevin Kelly, a violin maker in Boston who has handled dozens of Stradivarius instruments.Only about 600 of Stradivari’s masterpieces survive today, all prized by collectors and performers alike. A Stradivarius violin currently on the auction block — the first such sale in decades — is predicted to fetch up to $20 million.An 18th-century depiction of Antonio Stradivari, the Italian crafter of instruments.World History Archive/AlamyStradivari likely learned his craft by apprenticing with an older mentor, as was customary at the time. That could have been Amati, who, by the mid-17th century, was well established and also living in Cremona, a city in what is now Italy.“Some people assume that because Stradivari was Cremonese and he was such a great violin maker, he must have apprenticed with Amati,” said Mr. Kelly, who was not involved in the new study.But evidence of a link between Stradivari and Amati has remained stubbornly tenuous: One violin made by Stradivari bears a label reading “Antonius Stradiuarius Cremonensis Alumnus Nicolaij Amati, Faciebat Anno 1666.” That wording implies that Stradivari was a pupil of Amati, said Mr. Kelly, but it was the only label like it that has surfaced.With the goal of shedding on this musical mystery, Dr. Bernabei and his team visited the Museum of the Conservatory of San Pietro a Majella in Naples and analyzed the wood of a small harp made by Stradivari in 1681. Using a digital camera, the researchers precisely measured the widths of 157 tree rings visible on the instrument’s spruce soundboard.A small harp by Stradivari from 1681.DeAgostini/Getty ImagesThe pattern created by plotting the width of tree rings, one after the other, is like a fingerprint. This is because the amount that a trees grows each year depends on the weather, water conditions and a slew of other factors, Dr. Bernabei said. “Plants record very accurately what happens in their surroundings.”The researchers compared their measurements from the Stradivari harp with other tree ring sequences measured from stringed instruments. Out of more than 600 records, one stood out for being astonishingly similar: a spruce soundboard from a cello made by Nicola Amati in 1679. “All the maximum and minimum values are coincident,” Dr. Bernabei said. “It’s like somebody split a trunk in two different parts.”The same wood was indeed used to make the Stradivari harp and the Amati cello, Dr. Bernabei and his colleagues suggest. This was consistent with the two craftsmen sharing a workshop, with the elder Amati possibly mentoring the younger Stradivari, the team concluded.Perhaps that is true, said Mr. Kelly, but it is not the only possibility. Instead, Mr. Amati and Stradivari might simply have purchased wood from the same person, he said. After all, luthiers in 17th-and 18th-century Cremona belonged to a small community, said Mr. Kelly. “They basically all lived on the same street.” More

  • in

    You Hear the Musical Saw. These Mathematicians Heard Geometry.

    A scientist who has studied falling playing cards, coiling rope and other phenomena has now analyzed what transforms a carpenter’s tool into a sonorous instrument.Early in the 19th century, an unknown musician somewhere in the Appalachian Mountains discovered that a steel handsaw, a tool previously used only for cutting wood, could also be used to produce full and sustained musical notes. The idea had undoubtedly occurred to many a musically-inclined carpenter at other times in other places.The key is that the saw must be bent in a shallow S-shape. Leaving it flat, or bending it in a J- or U-shape, will not do. And to resonate, it must be bowed at exactly the right sweet spot along the length of the saw. Bowed at any other point, the instrument reverts to being a useful, but unmusical, hand tool.The seated musician grips the handle of the saw between her legs, and holds the tip with either her fingers or a device called an end clamp, or “saw cheat.” She bends the saw into a shallow S-shape, and then draws the bow across the sweet spot at a 90-degree angle with the blade. The saw is then bent, changing the shape of the S to lower or raise the pitch, but always maintaining the S-shape, and always bowed at the moving sweet spot of the curve. The longer the saw, the greater the range of notes it can produce.Now L. Mahadevan, a professor of physics and applied mathematics at Harvard, along with two colleagues, Suraj Shankar and Petur Bryde, has studied the way the saw produces music and drawn some conclusions that help explain, mathematically, its beautiful sounds. The report was published April 21 in the Proceedings of the National Academy of Science.Studying musical saws may seem an odd choice for a Harvard professor of mathematics, but Dr. Mahadevan’s interests are broad. He has published scientific papers explaining falling playing cards, tightrope walking, coiling rope, and how wet paper curls, among other phenomena that may appear at first glance unlikely subjects for mathematical analysis. In such a list, the musical saw seems no more than a logical next step.To understand the musical saw, imagine an S lying on its side, a line drawn through its center, positive above the line and negative below it. At the center of the S, he explained, the curvature switches its sign from negative to positive.“A simple change from a J- to an S-shape dramatically transforms the acoustic properties of the saw,” Dr. Mahadevan said, “and we can prove mathematically, show computationally, and finally hear experientially that the vibrations that produce the sound are localized to a zone where the curvature is almost zero.”That single location of sign-changing, he said, gives the saw a robust ability to sustain a note. The tone slightly resembles that of a violin and other bowed instruments, and some have compared it to the voice of a soprano singing without words.Dr. Mahadevan acknowledges that while he set out to understand the musical saw in mathematical terms, “Musicians have of course known this experientially for a long time, and scientists are only now beginning to understand why the saw can sing.”But he thinks research into the musical saw may also help scientists better understand other very thin devices.“The saw is a thin sheet,” he said, “and its thickness is very small compared to its other dimensions. The same phenomena can arise in a multitude of different systems, and might help design very high quality oscillators on small scales, and even perhaps with atomically thin materials such as sheets of graphene.” That could even be useful in perfecting devices that use oscillators, such as computers, watches, radios and metal detectors.For Natalia Paruz, a professional sawist who has played with orchestras worldwide, the mathematical details may be less significant than the quality of her saws. She began by playing her landlady’s saw when it wasn’t being used for other purposes. But now she uses saws specifically designed and manufactured to be used as musical instruments.There are several American companies that make them, and there are manufacturers in Sweden, England, France and Germany. Ms. Paruz said that while any flexible saw can be used to produce music, a thicker saw produces a “meatier, deeper, prettier” sound.But that pure tone, whatever its mathematical explanation, comes at a cost. “A thick blade,” she said, “is harder to bend.” More

  • in

    The Shakespearean Tall Tale That Shaped How We See Starlings

    Researchers debunked a long-repeated yarn that the common birds owe their North American beginnings to a 19th-century lover of the Bard. Maybe this ubiquitous bird’s story is ready for a reboot.In 1890, a mustachioed eccentric named Eugene Schieffelin released a few dozen European starlings into New York City. His supposed goal? Introduce all the bird species mentioned in William Shakespeare’s plays to America.More than a century later, the European starling is one of the most plentiful bird species in North America. Something like 85 million starlings inhabit this continent, from Alaska and Newfoundland all the way to Mexico. The animals are gorgeous, with polka-dot feather patterns and a purply-green sheen. They fill the skies in great numbers, flying in synchronized patterns called murmurations.But they are also considered a pest, said to spread disease to livestock and cause $800 million worth of agricultural damage each year. The species is believed to take over their nesting cavities, leading to population declines.Add it all up, and it makes one heck of a story about how even the tiniest of actions can trigger profound consequences. The butterfly effect, there for all to see in every roadside murmuration. A starling flaps its wings in Central Park, and around 130 years later, a woodpecker loses its nest and a dairy farmer loses their livelihood.“If true, it would suggest that a long-dead dramatist totally reshaped the ecosystem of a foreign continent, which is a fascinating connection between literature and science,” said John MacNeill Miller, an assistant professor of English at Allegheny College in Pennsylvania.However, Dr. MacNeill and a Lauren Fugate, a student who worked with him, recently concluded that crucial parts of the story are not true. And that made them wonder: What else have scientists and naturalists gotten wrong about the European starling’s narrative? Is there more to this bird known mostly as an invasive pest?The Bird and the Bard-LoverThree starlings collected in Central Park, including, from left, two juveniles collected in 1892 and an adult collected in 1890, in the American Museum of Natural History’s historical collection.Karsten Moran for The New York TimesFeathers of one of the European starling study skins from 1890. The museum’s starling collection includes specimens from their native, as well as introduced, range.Karsten Moran for The New York TimesDr. Miller has long been fascinated by the tale of Eugene Schieffelin. But there was a problem with the narrative.“In all the places that I had seen this story before,” he said, “I never saw a single reliable source from the time period when this supposedly happened.”So he and Ms. Fugate, started digging through archives and databases for any link between the Bard-lover and the bird. According to their findings, which were published in the journal Environmental Humanities in November, Schieffelin did release 40 pairs of European starlings into New York City twice in the springs of 1890 and 1891. But Ms. Fugate and Dr. Miller failed to find evidence that Schieffelin was the Shakespeare superfan he has been made out to be.They found in an essay collection published in 1948 that Edwin Way Teale, a Pulitzer Prize-winning nature writer, was the first to link the two. He referred to Schieffelin’s “curious hobby” of introducing “all the birds mentioned in the works of William Shakespeare.”Determined to find the source for Teale’s claim, Dr. Miller drove to the University of Connecticut to sort through a collection of Teale’s archives. (He died in 1980.) In a draft of the essay, Teale muses that perhaps Schieffelin had been influenced by a Shakespeare garden being started in Central Park around the same time — a botanical homage to the Bard that sought to nurture plants, not birds, mentioned in his plays.However, Teale got the timing wrong. The Shakespeare Garden — which you can still visit today — wasn’t planned until a decade after Schieffelin’s death, or 22 years after he first released starlings. Therefore, the garden could not have been a factor. The final version of the essay omitted the mention of the garden but left the connection between Schieffelin and Shakespeare. This statement of fact has since been repeated again and again without challenge in magazines, newspapers of record and birding websites.Several starlings in Fort Tryon park.Karsten Moran for The New York Times“Long story short, we concluded that this commonplace story is mostly fictional,” Dr. Miller said.Dr. Miller and Ms. Fugate also question whether today’s birds are uniquely descended from Schieffelin’s flocks, as is often parroted. Numerous records exist of earlier European starling introductions, starting in 1872, to locations including New York City, Ohio and even as far away as Oregon. Such releases were part of a movement at the time known as “acclimatization” where people deliberately experimented with transplanting species into new areas, either to see how they would adapt or because those species were seen as beneficial in some way.Some tellings of the Schieffelin starling origin story note these earlier introductions but suggest that those birds failed to survive. However, wild starlings were caught in Massachusetts in 1876, far from any of the documented introductions. Likewise, there is a record of wild starlings in New Jersey in 1884. And who knows how many birds truly survived in nature beyond human notice, the researchers argue.“From the perspective of an invasion biologist, most invasions come from multiple introductions,” said Natalie Hofmeister, a doctoral candidate at Cornell University.In 2019, Ms. Hofmeister published a study in the journal Molecular Ecology of the European starling’s genetic variation across North America. If all the birds came from Schieffelin’s small flock, then you’d expect to see a tight genetic bottleneck in the data. Likewise, if the other, earlier introductions had been successful, that should have injected more diversity into the results. But her findings landed somewhere in between.“It does seem like there’s a lot of ambiguity as to whether or not the New York birds were really the beginning of the starlings’ expansion,” said Ms. Hofmeister, who has a follow-up study in the works.Hell Is Empty and All the Starlings Are HereA scavenging starling near the southwest entrance to Central Park. Something like 85 million starlings inhabit North America — they are one of the most plentiful bird species on the continent.Karsten Moran for The New York TimesDr. Miller and Ms. Fugate also take issue with the depiction of starlings as biological terrors. As evidence, they point to a well-regarded study from 2003 that found out of 27 native cavity-nesting birds, only one showed hints of decline that might be attributed to the introduction of starlings: the small woodpeckers known as yellow-bellied sapsuckers.Nicole Michel, director of quantitative science for the National Audubon Society, sees it differently. It’s her job to drill down into bird population data. And she says looking for declines as a result of any one variable sets “too high of a bar.”“There are many factors out there that we know are impacting birds — cats, building collisions, pesticides,” she said. “And yet it’s very difficult to determine population level impacts.”She added: “So do starlings affect other birds? Definitely. Are they the only ones that affect other birds? No.”Nearly three billion birds have disappeared from North America since 1970. The European starlings here are counted among them, actually, with an estimated decline of 49 percent over the same time frame. (Starlings are also “declining rapidly” in Europe.)Even on the downswing, with about 85 million animals, starlings are bound to create an impact. The more likely scenario is that scientists don’t know enough to see the effects of starlings, said Daniel Simberloff, a biologist at the University of Tennessee.“We have no idea what its real impact is on insect populations, for example,” said Dr. Simberloff, who is also the editor of the journal Biological Invasions. Nor do scientists know much about more subtle but no less important impacts, such as the way starlings may affect how nutrients cycle through an ecosystem, he said.Anti-perching spikes are used to discourage birds, including starlings, from resting near the runways and taxiways at LaGuardia Airport.Karsten Moran for The New York TimesStarlings are believed to threaten native birds by taking over their nesting cavities, leading to population declines.Karsten Moran for The New York TimesOne factor that’s not subtle is the way European starlings descend on feedlots and dairy farms by the tens to hundreds of thousands. Starlings usually eat insects during the winter, but when livestock feed is available, they’ll pick through it for steam-flaked corn, which is higher in protein and fiber than other parts of the feed. And when that many birds are taking the M&Ms out of the trail mix, so to speak, it can affect growth and milk production in cows and cost dairy farmers millions of dollars, the U.S. Department of Agriculture estimates.The birds are also suspected of transmitting diseases to livestock, though proving how this happens exactly has been as slippery as deciphering the impacts on native birds. While feedlots with more starlings had higher incidences of antibiotic resistant E. coli, killing more than 70 percent of the starling flock did not change how much E. coli the cows had. It’s also unclear if starlings are bringing microbes into the feedlots or simply spreading microbes that are already there.A research economist for the U.S.D.A.’s National Wildlife Research Center, Stephanie Shwiff has seen how starlings congregate at dairy lots firsthand and, she said, it is “impressive.” But as she tallies up losses to the agricultural sector, she sees no redemptive arc for these birds — only financial harm.“A lot of producers know exactly the damage that the birds are doing, but they have this overwhelming sense that it’s just the cost of doing business,” Dr. Shwiff said. She said blueberry farmers and wine grape vineyards also get slammed: “They have an almost defeated attitude.”To help farmers and livestock owners, the U.S.D.A.’s Wildlife Services program helps disperse, relocate or eradicate starlings. In 2020 alone, the program shooed away nearly eight million European starlings, and killed another 790,128 of them. A vast majority of these animals were killed with a poison invented specifically for them called DRC-1339, or Starlicide.Starlings and Arrows of Outrageous FortuneJoan Berry Hale of Stockbridge, Ga., a survivor of a 1960 Eastern Airlines plane crash that was the result of a bird strike.Audra Melton for The New York TimesWhile starlings’ impact on native birds is still debated, no one can question the effect they’ve had on American aviation. Just ask Joan Berry Hale.On Oct. 4, 1960, Ms. Hale was working as a flight attendant for Eastern Airlines when the Lockheed L-188 Electra she was crewing scared a flock of starlings as it took off from Boston en route to Philadelphia.“I could see out the window in the back, and I saw all these black birds fly by,” said Ms. Hale, now 85. The plane’s propellers ingested hundreds of starlings, which disturbed the engines and forced the craft to pitch left and crash nose first into the bay. “They didn’t find the front-end crew until they pulled the nose up out of the mud the next day,” she recalled.Of the 72 people on board, only 10 survived. Most were severely injured, but Ms. Hale emerged unscathed and helped survivors exit the wreckage, put on life preservers and board rescue boats.The Electra crash remains the deadliest accident resulting from a bird strike in world history. It was also a turning point in aviation safety.“That was the crash that started it all,” said Carla Dove, program manager for the Smithsonian Institution’s Feather Identification Lab, which was created in response to the Electra accident.Since its formation, the Feather Identification Lab has worked with the Federal Aviation Administration to make air travel safer. Using the Smithsonian’s vast collection of feathers, Dr. Dove and other experts can take a piece of “snarge,” what they call bits of bird that have gone through a jet engine, and figure out which species it belonged to. Then, airport managers and wildlife biologists can work together to make the facilities less attractive to those species.For starlings, says Richard Dolbeer, a science adviser for the U.S.D.A.’s Airport Wildlife Hazards Program, something as simple as letting the grass grow can discourage the birds from landing. Spacing out trees also cuts down on large, communal overnight roosts that might keep the animals near an airport.This Great Breach in the Starling’s Abused NatureRyan Kronenbitter, the operations group supervisor for the team at LaGuardia Airport that helps manage wildlife.Karsten Moran for The New York TimesBut while starlings have caused plenty of wreckage to agriculture and aviation, the birds may have some admirable qualities that are typically overlooked.Dr. Simberloff, a pioneer in the field of invasion biology, said that it was a great tragedy that starlings had been introduced, but that some of the rhetoric around them is overblown.“You see a lot of these popular papers that talk about it as one of the great scourges of North America,” Dr. Simberloff said of starlings. “And they don’t seem to be that.”Dr. Dolbeer, who is also an ornithologist, said he had “great admiration for starlings because they are so adaptable.” He’s also fascinated by the way starlings can intermingle and even roost with native species, such as red-winged blackbirds. “It’s sort of like the analogy of America being a melting pot, with all the people coming in and gluing together,” he said.Dr. Simberloff said his daughter rescued a starling and raised it up from a chick. “It knows its name very clearly,” and will sometimes say it — Blue — when prompted, he said.There may even be reasons to further consider the birds’ ecological impact. The 2003 paper on starling dominance found three species of woodpeckers experienced population increases since the European birds arrived, although it does not make a case for causation. And Ms. Fugate and Dr. Miller point to a 1915 study by U.S.D.A. scientists who concluded that starlings gobbled up fewer crops and ate more crop pests than native species.And while his research has made the Shakespearean starling legend seem well and truly dead, the question of how to view the European starling these days seems very much to depend on whom you ask.After more than 60 years, Ms. Hale thinks about the crash anytime she sees a large flock of birds. So many innocent people lost their lives, and she’ll never forget the cold bite of the water. Ultimately, she thinks she became a better person because of the accident.And while she “doesn’t care much for those pesky birds,” she also doesn’t blame the European starling. “It wasn’t their fault,” Ms. Hale said. “That’s just nature.”A starling flaps its wings in Central Park, and a life changes course in the frigid waters of Boston Harbor.A starling undeterred by an anti-perching device on a lamppost at LaGuardia.Karsten Moran for The New York Times More

  • in

    New Report Paints Bleak Picture of Diversity in the Music Industry

    The Annenberg Inclusion Initiative examined 4,060 executives at six types of companies, and found 19.8 percent were from underrepresented racial and ethnic groups.A year ago, as protests spread across the country following the murder of George Floyd, the music industry promised to change.Major record labels, streaming platforms and broadcasters pledged hundreds of millions of dollars in charitable donations. The diversity of the music industry itself — a business that relies heavily on the creative labor of Black artists — came under scrutiny, with calls to hire more people of color and to elevate women and minorities into management and decision-making positions.But how diverse is the music business? The answer, according to a new study: not very.A report by the Annenberg Inclusion Initiative at the University of Southern California, released Tuesday, examined the makeup of 4,060 executives, at the vice president level and above, at 119 companies of six types: corporate music groups, record labels, music publishers, radio broadcasters, streaming services and live music companies.Among those executives, 19.8 percent were from underrepresented racial and ethnic groups, including 7.5 percent who were Black. Women made up 35.3 percent of the total.Delving deeper into the numbers, the authors of the 25-page report, led by Stacy L. Smith and Carmen Lee, found that the representation of women and minorities seemed to shrink as they looked higher up music companies’ organization charts.After filtering out subsidiaries, the researchers looked at the uppermost leadership positions — chief executives, chairmen and presidents — in a subset of 70 major and independent companies, and found that 86.1 percent of those people were both white and male. The 10 people of color who held those positions were all at independents, and just two were women: Desiree Perez, a longtime associate of Jay-Z who leads his company Roc Nation, and Golnar Khosrowshahi, the founder of Reservoir, which owns music rights.The report includes some stark findings. For example, among the 4,060 people in the study’s sample, the researchers found 17.7 white male executives for every Black female one.“Underrepresented and Black artists are dominating the charts, but the C-suite is a ‘diversity desert,’” Dr. Smith said in a statement. “The profile of top artists may give some in the industry the illusion that music is an inclusive business, but the numbers at the top tell a different story.”Each year since 2018, the Annenberg Inclusion Initiative has tracked the artists, songwriters and producers behind the biggest hits. Again and again, it has found that women are far outnumbered by men, yet revealed some encouraging numbers for underrepresented groups: People of color have made up about 47 percent of the credited artists behind 900 top pop songs since 2012.Yet the group’s new report, called “Inclusion in the Music Business: Gender & Race/Ethnicity Across Executives, Artists & Talent Teams,” and sponsored by Universal Music Group, shows that women and people of color are poorly represented in the power structure of the industry itself.The variation across different job levels and industry sectors is notable. Black executives fared best within record labels, making up 14.4 percent of all positions, and 21.2 percent of artist-and-repertoire, or A&R, roles, which tend to work most closely with artists. Black people hold just 4 percent of executive jobs in radio, and 3.3 percent in live music.According to U.S. census data, 13.4 percent of Americans identify as Black.Women posted their highest executive numbers in the live music business, holding 39.1 percent of positions. But drilling down, the study found, most of those women were white. Even at record labels, where Black executives were best represented, Black women held only 5.3 percent of executive jobs.The U.S.C. report is one of a number of efforts underway to examine the music industry and evaluate its progress in reaching stated goals of diversity and inclusion. This week, the Black Music Action Coalition, a group of artist managers, lawyers and other insiders, is expected to release a “report card” on how well the industry has met its own commitments to change.Much of the data used in the U.S.C. report, the researchers said, came from publicly available sources, like company websites. The report suggests that a lack of participation in the study by music companies was a reason.“Companies were given the opportunity to participate and confirm information, especially of senior management teams,” the report says. “Roughly a dozen companies did so. The vast majority did not.”The authors of the report, who also include Marc Choueiti, Katherine Pieper, Zoe Moore, Dana Dinh and Artur Tofan, said they want to spur the industry toward change. The report recommends a number of steps that companies can take to make their executive ranks more diverse, including making career pathways more flexible and “fast tracking” leaders with support and mentoring.“Our hope,” Dr. Lee said, “is that the industry will come together to tackle this problem in a way that creates meaningful progress.” More

  • in

    Stereotypes Are Rife Among Asian and Pacific Islander Film Roles, Study Finds

    Two-thirds of characters reflect stereotypes, and just 3.4 percent of movies had leads or coleads who were Asians or Pacific Islanders, the study of 1,300 movies found.Of the 1,300 top-grossing films released from 2007 through 2019, just 44 featured an Asian or Pacific Islander character in a leading role — and one-third of the roles went to a single actor, Dwayne Johnson, a study has found. More

  • in

    Hear the Sound of a Seashell Horn Found in an Ancient French Cave

    AdvertisementContinue reading the main storySupported byContinue reading the main storyTrilobitesHear the Sound of a Seashell Horn Found in an Ancient French CaveMusic from the large conch probably hadn’t been heard by human ears for 17,000 years.The shell of Charonia lampas recovered from the Marsoulas cave in the Pyrenees of France.Credit…C. Fritz, Muséum d’Histoire naturelle de ToulouseFeb. 10, 2021Updated 5:10 p.m. ETIn 1931, researchers working in southern France unearthed a large seashell at the entrance to a cave. Unremarkable at first glance, it languished for decades in the collections of a nearby natural history museum.Now, a team has reanalyzed the roughly foot-long conch shell using modern imaging technology. They concluded that the shell had been deliberately chipped and punctured to turn it into a musical instrument. It’s an extremely rare example of a “seashell horn” from the Paleolithic period, the team concluded. And it still works — a musician recently coaxed three notes from the 17,000-year-old shell.Listen to a Recording of the Seashell HornWhen the conch was played by a musician, it produced notes that were similar to C, C-sharp, and D.“I needed a lot of air to maintain the sound,” said Jean-Michel Court, who performed the demonstration and is also a musicologist at the University of Toulouse.The Marsoulas Cave, in the foothills of the French Pyrenees, has long fascinated researchers with its colorful paintings depicting bison, horses and humans. It’s where the enormous tan-colored conch shell was first discovered, an incongruous object that must have been transported from the Atlantic Ocean, over 150 miles away.Despite its heft, the shell, from the sea snail Charonia lampas, gradually slipped into oblivion. Presumed to be nothing more than a drinking vessel, the conch sat for over 80 years in the Natural History Museum of Toulouse.Another view of the shell.Credit…C. Fritz and G. ToselloA conch from New Zealand and its mouthpiece made of a decorated bone tube.Credit…Musée du Quai Branly, Jacques ChiracOnly in 2016 did researchers begin to analyze the shell anew. Artifacts like this conch help paint a picture of how cave dwellers lived, said Carole Fritz, an archaeologist at the University of Toulouse who has been studying the cave and its paintings for over 20 years. “It’s difficult to study cave art without cultural context.”Dr. Fritz and her colleagues started by assembling a three-dimensional digital model of the conch. They immediately noticed that some parts of its shell looked peculiar. For starters, a portion of its outer lip had been chipped away. That left behind a smooth edge, quite unlike Charonia lampas, said Gilles Tosello, a prehistorian and visual artist also at the University of Toulouse. “Normally, they’re very irregular.”The apex of the conch was also broken off, the team found. That’s the most robust part of the shell, and it’s unlikely that such a fracture would have occurred naturally. Indeed, further analysis showed that the shell had been struck repeatedly — and precisely — near its apex. The researchers also noted a brown residue, perhaps remnants of clay or beeswax, around the broken apex.The mystery deepened when the team used CT scans and a tiny medical camera to examine the inside of the conch. They found a hole, roughly half an inch in diameter, that ran inward from the broken apex and pierced the shell’s interior structure.An ancient painting in Marsoulas cave. Credit…C. Fritz and G. ToselloAll of these modifications were intentional, the researchers believe. The smoothed outer lip would have made the conch easier to hold, and the broken apex and adjacent hole would have allowed a mouthpiece — possibly the hollow bone of a bird — to be inserted into the shell. The result was a musical instrument, the team concluded in their study, which was published Wednesday in Science Advances.This shell might have been played during ceremonies or used to summon gatherings, said Julien Tardieu, another Toulouse researcher who studies sound perception. Cave settings tend to amplify sound, said Dr. Tardieu. “Playing this conch in a cave could be very loud and impressive.”It would also have been a beautiful sight, the researchers suggest, because the conch is decorated with red dots — now faded — that match the markings found on the cave’s walls.This discovery is believable, said Miriam Kolar, an archaeoacoustician at Amherst College in Massachusetts who studies conch horn shells but was not involved in the research. “There’s compelling evidence that the shell was modified by humans to be a sound-producing instrument.”While other “seashell horns” have been found in places like New Zealand and Peru, none are as old as this conch.Dr. Fritz said it was incredible to hear Dr. Court play the conch. Its music hadn’t been heard by human ears for many millenniums, which made the experience particularly moving, she said.“It was a fantastic moment.”AdvertisementContinue reading the main story More